Na hmuhtonnak tthanchoter awkah cookies kan hman. Hi website na zoh peng ahcun, kan hmanmi cookies kha na cohlan. Thawngpang tam deuh.
“Allow All” na hmeh ahcun, na thilri ah cookies chiahnak kha na cohlan i cu nih cun website kalnak tthanchoter, website hmannak hlathlainak tuah, le man loin, on khawhmi scientific konglam kan pekmi bawmhchanh a si. Thawngpang tam deuh.
Zun cheknak sawhsawh nih Alzheimer zawtnak a hramthawk tein a hmuh khawh lai maw, mibu cheknak program caah lam a onh khawh lai maw? Frontiers in Aging Neuroscience hlathlainak thar nih mah cu a langhter hrimhrim. Hlathlaitu hna nih zunthlum biomarkers aa dannak hmuh khawhnak ding caah a fah ning aa dangmi le a ngandammi minung phu nganpi kha an hneksak hna.
Zun chung i a ummi formic acid cu mi pakhat cio nih an hngalh khawhnak a zorter i Alzheimer zawtnak a hramthawknak a langhter kho tiah an hmuh. Alzheimer zawtnak thlopnak caah a um cangmi lam hna cu a man a fak, a fawi lo, cun a zungzal in cheknak tuah khawh a si lo. A sullam cu mizaw tam deuh cu thlopbulnak ttha hmuh khawhnak ding caah a tlai tuk tikah lawng an zawtnak an hmuh hna tinak a si. Sihmanhsehlaw, a luhhnawh lomi, a man a fawimi le a fawimi formic acid caah zunthlum cheknak cu sibawi te nih tuan tein cheknak caah an halmi a si kho men.
“Alzheimer zawtnak cu a hmunmi le a thli tein a ummi zawtnak a si, a sullam cu a langhnganmi thluak lei tlamtlin lonak a chuah hlanah kum tampi chung a chuak kho i a hmun kho,” tiah catialtu hna nih an ti. “Zawtnak a hramthawknak cu thlen khawh lomi lungfimlonak dirhmun hlan ah a cang, cucu thlopbulnak le thlopnak caah sui thlalang a si. Cucaah, tar pawl ah a hramthawknak Alzheimer zawtnak caah a nganmi cheknak tuah a herh.”
Cucaah, tuan tein thlopbulnak tuah a biapi ahcun, zeicahdah tuan tein Alzheimer zawtnak caah thlopbulnak program kan ngeih lo? Buainak cu a tu lio sibawi te nih an hmanmi zawtnak thlopnak lam ah a um. Cu hna ah cun thluak positron emission tomography aa tel, mah cu a man a fak i mizaw hna kha radiation a pek hna. Alzheimer zawtnak a hmuh khawhmi biomarker hneksaknak zong an um, asinain thluak chung ti hmuh khawhnak ding caah a luhhnawhmi thi laknak asiloah hngawng hliamhma a herh, cucu mizaw nih an hngah men lai.
Sihmanhsehlaw, zunthlum cheknak cu a luhhnawh lomi le a fawimi a si caah mibu cheknak caah a ttha tukmi a si. Hlathlaitu hna nih Alzheimer zawtnak caah zunthlum biomarkers an rak hmuh cang ko nain, zawtnak a hramthawknak hmuh khawhnak caah pakhat hmanh aa tlak lo, a sullam cu thlopnak hmasa bik caah sui thlalang cu hmuh khawh a si rih lo tinak a si.
Hlathlainak thar a tuahtu hna nih a hlan ah Alzheimer zawtnak caah zunthlum biomarker ah formaldehyde timi organic compound kha an rak hlathlai cang. Sihmanhsehlaw, zawtnak hngalh khawhnak ah tthanchonak a um rih. Hi hlathlainak thar bik ah, annih nih formaldehyde thlennak a simi formate kha biomarker ah a ttha deuh maw ttha lo ti zoh awkah an zoh.
Hlathlainak ah minung 574 an i tel, cun aa telmi hna cu thluak lei in a ttha ngaimi volunteer an si asiloah zawtnak a karhning aa dangmi an si, thluak lei ttumchuknak in zawtnak tling tiang. Hlathlaitu hna nih aa telmi hna zun le thi an zohfel hna i lungthin lei zohfelnak an tuah.
Hlathlainak nih a hmuhmi cu zunthlum formic acid dat cu Alzheimer zawtnak phu vialte ah a sang ngaingai i a ngandammi control pawl he tahchunh tikah thluak tthawnnak a zornak he aa pehtlai, a hmasa bik thluak tthawnnak a zormi phu zong aa tel. Mah nih hin formic acid cu Alzheimer zawtnak a hramthawknak caah a biapi tukmi hmelchunhnak pakhat a si kho tiah a langhter.
Hngalh a nuammi cu, hlathlaitu hna nih zunthlum formate dat le Alzheimer's thisen biomarkers fonh in an hlathlai tikah, mizaw pakhat nih a tonmi zawtnak dirhmun kha a dikthliar in an chimchung khawh ti kha an hmuh. Sihmanhsehlaw, Alzheimer zawtnak le formic acid karlak pehtlaihnak hngalhthiam awkah hlathlainak tuah chap a hau.
“Zuin formic acid nih Alzheimer zawtnak hngalh khawhnak ding caah a ttha tukmi a langhter,” tiah catialtu hna nih an ti. “Alzheimer zawtnak caah zunthlum biomarker hneksaknak cu a fawi i a man a fawi i tar pawl caah ngandamnak zohfelnak ah aa tel awk a si.”
Wang, Y. le a dangdang. (2022) Alzheimer zawtnak caah a thar in a chuak khomi zunthlum formic acid kha ningcang tein zohfelnak. Tarnak thluak lei ah ramri. doi.org/10.3389/fnagi.2022.1046066.
Tags: tarnak, Alzheimer zawtnak, biomarkers, thisen, thluak, a hmunmi, a hmunmi zawtnak, compound, lungfim lonak, zawtnak thlopnak, sibawi, formaldehyde, thluak lei, positron emission tomography, hlathlainak, tomography, zunthlum cheknak
Philadelphia, Pennsylvania ah tuahmi Pittcon 2023 ah, tukum Ralph N. Adams Prize in Analytical Chemistry a hmumi Professor Joseph Wang kha biosensor thiamnak a phunphun kong he pehtlai in bia kan hal.
Hi biahalnak ah, Owlstone Medical ah Team Leader a simi Mariana Leal he thawchuahnak biopsy kong le zeitindah zawtnak hngalh khawhnak caah biomarkers hlathlainak caah thilri ttha a si khawh timi kong kan i ruah.
Kan SLAS US 2023 zohfelnak ah aa telmi pakhat in, hmailei laboratory kong le zeitindah a lawh lai timi kong kha GSK Test Development Team Hruaitu Luigi Da Via he kan i ruah.
News-Medical.Net nih hi phunglam le sining hna ningin hi sii lei thawngpang riantuannak hi a pek. Hi website chung i sii lei konglam hna cu mizaw sibawi/sibawi pehtlaihnak le an pek khawhmi sii lei ruahnak cheuhnak bawmhchanh ding le aiawh ding in timhmi a si lo ti kha philh hlah.